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Molecular genetic analysis of circadian clocks Steve A. Kay* 10550 North Torrey Pines Road, BCC 265, La Jolla CA 92037, USA      *(stevek@scripps.edu) Our laboratory is interested in understanding the interactions between phototransduction pathways and the circadian clock in controlling plant growth and development. Using cab-luciferase transgenic lines as bioluminescent markers, we are undertaking several different approaches that will be discussed: 1) Identification and characterization of novel circadian rhythm mutants by screening for aberrant period length (toc) mutants. Two of these are currently being characterized in detail. 2) Genetic analysis of photoreceptor-clock interactions using a wide range of photoreceptor/phototransduction mutant backgrounds. 3) Genetic analysis of the role of the circadian clock in the photoperiodic control of flowering time. 4) Analysis of DNA-protein interactions mediating clock- and phytochrome-controlled gene transcription. 5) Identification of novel markers for clock regulation at different stages of development and in different tissues. We will discuss how these approaches have revealed a central role for the circadian clock in controlling a wide range of plant metabolic and developmental processes. [Talk: kay.stevea.50531]

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