MCDB Home > Faculty > Dennis Clegg > Selected Publications

Clegg, D.O. (1993) Characterization of a beta-nerve growth factor expression vector for mammalian cells. Gene, 130:291-296.

Choi, E.S-H., Rettig, W.J., Wayner, E.A., Srour, M. L. and Clegg, D.O. (1994) Functional identification of integrin laminin receptors that mediate process outgrowth in human SY5Y neuroblastoma cells. J. Neurosci. Res., 37:475-488.

Raichman, M., Panzeri, M.C., Clementi, E., Papazafiri, P., Eckley, D.M., Clegg, D.O., Villa, A. and Meldolesi, J. (1995) Differential localization and functional role of calsequestrin in growing and differentiated myoblasts. J. Cell. Biol., 128:341-354.

Bradshaw, A.D., McNagny, K.M., Gervin, D.B., Cann, G.M., Graf, T., and Clegg, D.O. (1995) Integrin alpha-2/beta-1 mediates interactions between developing embryonic retinal cells and collagen. Development, 121:3593-3602.

Gervin, D.B., Cann, G.M., and Clegg, D.O. (1996) Temporal and spatial regulation of integrin vitronectin receptor mRNAs in the embryonic chick retina. Invest. Ophthal. Vis. Sci., 37:1084-1096.

Cann, G.M., Bradshaw, A.D., Gervin, D.B., Hunter, A.W. and Clegg, D.O. (1996) Widespread expression of beta-1 Integrins in the Developing Chick Retina: Evidence for a role in migration of retinal ganglion cells. Dev. Biol., 180:82-96.

Lin, H. and Clegg, D.O. (1998) Integrin alpha-v/beta-5 participates in the phagocytosis of photoreceptor rod outer segments by cultured human retinal pigment epithelium. Invest. Ophthal. Vis. Sci., 39:1703-1712.

Chen, C.H., Clegg, D.O. and Hansma, H. (1998) Structures and dynamic motion of laminin-1 as observed by atomic force microscopy. Biochemistry, 37:8262-8267.

Kil, S.H., Krull, C.E, Cann, G.M., Clegg, D.O. and Bronner-Fraser, M. (1998) The integrin alpha-4 subunit is important for neural crest cell migration. Dev. Biol., 202:29-42.

Lin, H., Clegg, D. O. and Lal, R. (1999) Imaging real time proteolysis of single collagen I molecules with an atomic force microscope. Biochemistry, 38:9956-63.

Clegg, D.O. (1999) Extracellular Matrix, in The Encyclopedia of Molecular Biology, John Wiley and Sons, NY.

Clegg, D.O., Mullick, L.H., Wingerd, K., Lin, H., Atienza, J., Bradshaw, A.D., Gervin, D.B. and Cann, G.M. (2000) Adhesive events in retinal development and function: The role of integrin receptors, in Results and Problems in Cell Differentiation: Vertebrate Eye Development, E. Fini, ed., Springer-Verlag, Berlin, 3:141-156

Clegg, D.O. (2000) Novel roles for integrins in the nervous system, Mol. Cell Biol. Rapid Comm., 3:1-7.

Lin, H., Lal, R. and Clegg, D. O. (2000) Imaging and mapping heparin-binding sites on single fibronectin molecules with atomic force microscopy. Biochemistry, 39:3192-6.

Leonoudakis, D., Mailliard, W. S., Wingerd, K. L., Clegg, D. O. and Vandenberg, C.A. (2001) Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97, J. Cell Sci., 114:987-998.

Culley, B., Murphy, J., Babaie, J., Nguyen, D., Rousselle, P. and Clegg, D. O. (2001) Laminin-5 promotes neurite outgrowth from central and peripheral chick embryonic neurons, Neurosci. Letters, 301:83-86.

Clegg, D.O. (2001) Extracellular Matrix, Laminins, Elastin, in The Encyclopedia of Molecular Medicine, Thomas Creighton, ed., John Wiley and Sons, NY.

Leu, S.T., Batni, S., Radeke, M.J., Johnson, L.V., Anderson, D.H. and Clegg, D.O. (2002) Drusen are cold spots for proteolysis: Expression of matrix metalloproteinases and their tissue inhibitor proteins in age-related macular degeneration. Exptl. Eye Res., 74:141-154.

Mey, A., Gandrillon, O., McNagny, K.M., Clegg, D. O. and Samarut, J. (2002) Role of the alpha-2/beta-1 integrin in erythrocytic progenitors proliferation and its abrogation by the v-erbA oncogene. Oncogene, 21:2864-2872.

Wingerd, K.L., Goodman, N.L., Smail, M.L., Rohan, S.J., Leu, S.T. and Clegg, D.O. (2002) alpha-4 integrins and VCAM-1 play a role in sympathetic innervation of the heart. J. Neurosci., 22:10772-80.

Hansma, H., Tirrel, M. and Clegg, D.O. (2002) Analysis of Extracellular matrix Dynamics by Atomic Force Microscopy. Methods in Cell Biology. 69:163-93.

Hikita, S.T., Cann, G.M, Wingerd, K.L., Mullick, L.H., Wayne, W.C., Webb, S.W. and Clegg, D.O. (2003) Integrin alpha-4/beta-1 (VLA-4) expression and activity in retinal and peripheral neurons. Mol. Cell. Neurosci., 23:427-39.

Clegg, D.O., Wingerd, K.L, Hikita, S. and Tolhurst, E.C. (2003) Integrins in the development, function and dysfunction of the nervous system. Frontiers in Bioscience, 8:d723-750.

Wingerd, K. L., Goodman, N. L., Leu, S. T., and Clegg, D. O. (2004) Expression and function of integrin a4b1 and vascular cell adhesion molecule-1 (VCAM-1) during sympathetic innervation of the heart. Developmental Dynamics, 231: 359-69.

Leu, S. T., Jacques, S. A. L., Wingerd, K. L., Hikita, S. T., Pring, J. L., Wiswell, D., Kinney, L., Goodman, N. L., Jackson, D. Y., and Clegg, D. O. (2004) Integrin alpha4beta1 function is involved in cell survival in developing retina. Developmental Biology. 276:416-430.

Wingerd KL, Wayne WC, Jackson DY, Clegg DO. (2005) Involvement of alpha4 integrins in maintenance of cardiac sympathetic axons. Auton Neurosci. 122(1-2):58-68.

Putzke AP, Hikita ST, Clegg DO, Rothman JH. (2005) Essential kinase-independent role of a Fer-like non-receptor tyrosine kinase in Caenorhabditis elegans morphogenesis. Development, 132(14):3185-95.