MCDB Home > Faculty > Stuart Feinstein > Selected Publications

Bunker, J., Jordan, M.A., Wilson, L. and Feinstein, S.C. (2006) FTDP-17 Mutations Decrease The Ability Of Tau To Stabilize Microtubule Dynamics In Living Cells Journal of Biological Chemistry doi:10.1074/jbc.M509420200

Levy SF, Leboeuf AC, Massie MR, Jordan MA, Wilson L, Feinstein SC. (2005) Three- and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners. Implications for neurodegeneration. J Biol Chem.280(14):13520-8.

Gaylord BS, Massie MR, Feinstein SC, Bazan GC. (2004) SNP detection using peptide nucleic acid probes and conjugated polymers: applications in neurodegenerative disease identification. Proc Natl Acad Sci U S A. 102(1):34-9. El Saban, M., Altinok, A., Peck, A., Kenney, C. Feinstein, S.C., Wilson, L., Rose, K. and Manjunath, B. (2006) Automated Tracking and Modeling of Microtubule Dynamics. Proceedings of the International Symposia on Biological Imaging.

Bunker, J., Jordan, M.A., Wilson, L. and Feinstein, S.C. (2004) Modulation of Microtubule Dynamics by Tau in Living Cells: Implications for Development and Neurodegeneration. Molecular Biology of the Cell 15:2720-8272

Makrides, V., Massie, M., Feinstein, S.C. and Lew, J. (2004) Evidence for Two Distinct Binding Sites for Tau on Microtubules Proceedings of the National Academy of Sciences USA 101:6746-6751

Feinstein, S.C. and Wilson, L. (2004) Inability of Tau to Properly Regulate Neuronal Microtubule Dynamics: A Loss-of-Function Mechanism by which Tau Might Mediate Neuronal Cell Death. BBA:Molecular Basis of Disease (In press)

Gaylord, B.S., Massie, M.R., Feinstein, S.C. and Bazan, G.C. (2004) Optically Enhanced Single Nucleotide Polymorphism Detection Using Peptide Nucleic Acid Probes and Conjugated Polymers: Applications in Neurodegenerative Disease Identification Proceedings of the National Academy of Sciences USA. (in press)

Panda, D., Samuel, J.C., Massie, M., Feinstein, S.C. and Wilson, L. (2003) Differential Regulation of Microtubule Dynamics by 3-Repeat and 4-Repeat Tau: Implications for Normal Neuronal Development and the Onset of Neurodegenerative Disease. Proceedings of the National Academy of Sciences USA 100:9548-9553.

Makrides, V., Shen, T.E., Bhatia, R., Smith, B.L., Thimm, J., Lal, R. and Feinstein, S.C. (2003) Microtubule Dependent Oligomerization of Tau: Implications for Physiological Tau Function and for Tauopathies. Journal of Biological Chemistry 278:33298-33304

Zhukareva, V. Mann, D., Uryu, K., Shuck, T., Shah, K., Grossman, M., Miller, B.L., Hulette, C.M., Feinstein, S.C., Trojanowshi, J.Q. and Lee, V.M-Y. (2002) Sporadic Pick's Disease: A Tauopathy Characterized by a Spectrum of Gray and White Matter Pathological Tau Isoforms. Annals of Neurology (51:730-739)

Goode, B.L., Chau, M., Denis, P.E. and Feinstein, S.C. (2000) Structural and Functional Differences Between 3-Repeat and 4-Repeat Tau Isoforms: Implications for Normal Tau Function and the Onset of Neurodegenerative Disease. Journal of Biological Chemistry 275:38182-38189

Giannetti, A.M., Lindwall, G., Chau, M.F., Radeke, M.J., Feinstein, S.C. and Kohlstaedt, L.A. (2000) Fibers of tau fragments, but not full length tau, exhibit a cross beta diffraction pattern: Implications for the formation of paired helical filaments. Protein Science 9:2427-2435.

McCarty, J.H. and Feinstein, S.C. (1999) The TrkB Receptor Tyrosine Kinase Regulates Cellular Proliferation via Signal Transduction Pathways Involving Shc, PLC? and Cbl. Journal of Receptor and Signal Transduction Research 19:953-974.

Chau, M-F, Radeke, M.J., Barasoain, I. de Ines, C., Kohlstaedt, L.A. and Feinstein, S.C. The microtubule associated protein tau cross-links to two distinct sites on each a and b monomer via seperate domains. Journal of Biological Chemistry 275:38182-38189

McCarty, J.H. and Feinstein, S.C. (1998) Activation Loop Tyrosines Contribute Varying Roles to TrkB Autophosphorylation and Signal Transduction. Oncogene 16:1691-1700.

Baxter, G., Radeke, M.J., Kuo, R., Makrides, V., Hinkle, B., Medina-Selby, A., Coit, D., Valenzuela, P. and Feinstein, S.C. (1997) Signal Transduction by the Neural Truncated trkB Isoforms, trkB.T1 and trkB.T2. Journal of Neuroscience 17:2683-2690.

Goode, B., Denis, P., Panda, D., Miller, H., Radeke, M.J., Wilson, L. and Feinstein, S.C. (1997) Functional Interactions between the Proline-rich and Repeat Regions of Tau Enhance Microtubule Binding and Assembly. Molecular Biology of the Cell 8:353-365.

Yan, Q. , Radeke, M.J., Matheson, C.R., Talvenheimo, J., Welcher, A.A. and Feinstein, S.C. (1997) Immunocytochemical localization of trkB in Central Nervous System of the Adult Rat. Journal of Comparative Neurology 378:135-157. (Addition of missing references; 382:546-547).

Cabelli, R.J., Allendoerfer, K.L., Radeke, M.J., Feinstein, S.C. and Shatz, C.J. (1996) Changing Patterns of Expression and Subcellular Localization of trkB in the Developing Visual System. Journal of Neuroscience 16:7965-7980

Fryer, R.H., Kaplan, D.R., Feinstein, S.C., Radeke, M.J., Grayson, D.R. and Kromer, L.R. (1996) Developmental and Mature Expression of Full-Length and Truncated TrkB Receptors in the Rat Forebrain. Journal of Comparative Neurology 374:21-40.

Panda, D. Goode, B.L., Feinstein, S.C. and Wilson, L. (1995) Kinetic Stabilization of Microtubule Dynamics at Steady State by Tau and Microtubule Binding Domains of Tau. Biochemistry 34:11117-11127.

Lal, R., Drakes, B., Blumberg, D., Saner, D., Hansma, P.K. and Feinstein, S.C. (1995) Imaging Neurite Outgrowth and Cytoskeletal Reorganization with an Atomic Force Microscope: Studies on PC12 and NIH3T3 Cells. American Journal of Physiology 38:275-285.

Goode, B.L. and Feinstein, S.C., (1994) Identification of a Novel Microtubule Binding and Assembly Domain in the Developmentally Regulated, Inter-Repeat Region of Tau. Journal of Cell Biology 124:769-782.

Esmaeli-Azad, B., McCarty, J. and Feinstein, S.C. (1994) Sense and Antisense Transfection Analysis of Tau Function: Tau Is a Limiting Factor for Neurite Outgrowth and Provides Structural Stability to Neuronal Processes. Journal of Cell Science 107:869-879.