MCDB Home > Faculty > Cyrus Safinya > Selected Publications

Cationic Liposome-DNA Complexes: From Liquid Crystal Science to Gene Delivery Applications. C. R. Safinya, K. Ewert, A. Ahmad, H. M. Evans, Uri Raviv, A. J. Lin, N. L. Slack, C. George, C. E. Samuel, (Philosophical Transactions of the Royal Society, in press)

A Columnar Phase of Dendrimer based Cationic Liposome-DNA Complexes for Gene Delivery: Hexagonally Ordered Cylindrical Micelles embedded in a DNA Honeycomb Lattice. Kai Ewert, Heather Evans, N. Bouxsein, A. Ahmad, C. R. Safinya, J. Am. Chem. Soc., 128 (12) 3998-4006 (2006).

Cationic Liposome - Microtubule Complexes: Pathways to the Formation of Two State Lipid-Protein Nanotubes with Open or Closed Ends. U. Raviv, D. J. Needleman, Y. Li, H. P. Miller, L. Wilson, and C. R. Safinya, Proceedings of the National Academy of Sciences USA 102 (32), 11167-11172 (2005).

Radial Compression of Microtubules by Osmotic Pressure and the Mechanism of Action of Taxol and Microtubule Associated Proteins. Daniel J. Needleman, Uri Raviv, Miguel Ojeda-Lopez, Herbert P. Miller, Leslie Wilson, and C. R. Safinya, Biophysical Journal 89, 3410-3423 (2005).

A microchannel system in titanium and silicon for structural and mechanical studies of aligned protein self assemblies. L. S. Hirst, E. R. Parker, Z. Abu Samah, Y. Li, N. C. MacDonald, and C. R. Safinya, Langmuir 21, 3910-3914 (2005).

Cationic lipid-DNA complexes for non-viral gene therapy: relating supramolecular structures to cellular pathways. Kai Ewert, Ayesha Ahmad, Heather Evans, Cyrus R. Safinya, Expert Opinion on Biological Therapy 5(1), 33-53 (2005).

New Multivalent Lipids Reveal Bell-Curve for Transfection versus Membrane Charge Density: Nonviral Lipid-DNA Complexes for Gene Delivery, Ayesha Ahmad, Heather Evans, Kai Ewert, C. X. George, Charles E. Samuel, Cyrus R. Safinya, Journal of Gene Medicine 7, 739-748 ( 2005)

Higher Order Assembly of Microtubules by Counter-ions: From Hexagonal Bundles to Living Necklaces . by Daniel J. Needleman, Miguel Ojeda-Lopez, Uri Raviv, Herbert P. Miller, Leslie Wilson, and Cyrus R. Safinya, Proceedings of the National Academy of Sciences USA, 101 (46), 16099-16103 (2004).

Ordered Patterns of Liquid Crystal Toroidal Defects by Microchannel Confinement.by Myung Chul Choi, Thomas Pfohl, Zhiyu Wen, Youli Li, Mahn Won Kim, Jacob N. Israelachvili, and Cyrus R. Safinya, Proceeding of the National Academy of Sciences USA, 101 (50), 17340-17344 (2004).

Three-dimensional Imaging of Lipid Gene-Carriers: Membrane Charge Density Controls Universal Transfection Behavior in Lamellar Cationic Liposome-DNA Complexes. Alison Lin, Nelle Slack, Ayesha Ahmad, Cyil George, Chuck Samuel, C. R. Safinya, Biophysical J. 84 (5), 1-10 (2003).