The Rothman Lab
NEUROSCIENCE RESEARCH INSTITUTE
and DEPARTMENT OF MOLECULAR, CELLULAR and DEVELOPMENTAL BIOLOGY
UC SANTA BARBARA, SANTA BARBARA, CA 93106
Ling Chen
Postdoc

l_chen@lifesci.ucsb.edu

Publications

 

  • Chen L, McCloskey T, Joshi PM, Rothman JH (2008). CED-4 and proto-oncogene TFG-1 antagonistically regulate cell size and apoptosis in C. elegans. Current Biology. 18(14):1025-33.
  • Chen L, Trujillo KM, Van Komen S, Roh DH, Krejci L, Lewis LK, Resnick MA, Sung P, Tomkinson AE (2005) Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast. Journal of Biological Chemistry. 280(4):2620-7. Abstract
  • Trujillo, K, Roh, DH, Chen, L, Tomkinson, A, and Sung, P (2003) Yeast Xrs2 protein binds DNA and is essential for targeting Rad50 and Mre11 to DNA ends. Journal of Biological Chemistry, 278(49): 48957-48964.  Abstract
  • Krejci, L, Chen, L, Van Komen, S, Sung, P, and Tomkinson, AE (2003) Mending the break: two repair machines in eukaryotes. Progress in Nucleic Acid Research and Molecular Biology, 74:159-201. Abstract
  • Tomkinson, AE, Chen, L, Dong, Z, Leppard, JB, Levin, DS, Mackey, ZB and Motycka, TA (2001) Completion of Base Excision Repair by Mammalian DNA Ligases. Progress in Nucleic Acid Research and Molecular Biology, Vol. 68:151-164.  Abstract
  • Chen, L, Trujillo, K, Ramos, W, Sung, P, and Tomkinson, AE (2001) Promotion of Dn14-mediated DNA End Joining by the Rad50/Mre11/Xrs2 Complex. Molecular Cell 8(5):1105-1115.  Abstract
  • Chen, L, Trujillo, K, Sung, P, and Tomkinson, AE (2000) Interaction of the DNA Ligase IV/Xrcc4 Complex with DNA Ends and the DNA-dependent Protein Kinase. Journal of Biological Chemistry, 275(34):26196-26205.  Abstract
  • Dimitriadis, EK, Prasad, R, Vaske MK, Chen, L, Tomkinson, AE, Lewis, MS and Wilson, SH (1998) Thermodynamics of Human DNA Ligase I Trimerization and Association with DNA Polymerase. Journal of Biological Chemistry, 273(32):20540-20550.   Abstract
  • Rodriguez, K, Talamantez, J, Huang, W, Reed, SH, Wang, Z, Chen, L, Feaver, WJ, Friedberg, EC and Tomkinson, AE (1998) Affinity Purification and Partial Characterization of a Yeast Multiprotein Complex for Nucleotide Excision Repair Using Histidine-tagged Rad14 Protein. Journal of Biological Chemistry, 273(51):34180-34189.  Abstract