THE UNIVERSITY OF TOKYO
Kenji Kontani

kontani@mol.f.u-tokyo.ac.jp

 

Rothman Lab Publications

 

Earlier Publications

  • Nishida, M., Maruyama, Y., Tanaka, R., Kontani, K., Nagao, T., and Kurose, H. (2000) G alpha(i) and G alpha(o) are target proteins of reactive oxygen species. Nature 408, 492-4950.  Abstract
  • Kuroda, R., Kontani, K., Kanda, Y., Katada, T., Satoh, Y., Suzuki, N., and Kuroda, H. (2000) Role of guanylyl cyclase in fertilisation of sea urchin eggs. Zygote 8, S18-19.  Abstract

 

  • Katada, T., Kontani, K., Wada, T., Hosoda, N., Hoshino, S., and Nishina, H. (2000) Enzymic and signal transduction properties of CD38/NADase and PC-1/phosphodiesterase. Chem. Immunol. 75, 60-78. 
  • Katada, T., Kurosu, H., Okada, T., Suzuki, T., Tsujimoto, N., Takasuga, S., Kontani, K., Hazeki, O., and Ui, M. (1999) Synergistic activation of a family of phosphoinositide 3-kinase via G-protein coupled and tyrosine kinase-related receptors. Chem. Phys. Lipids. 98, 79-86.  Abstract
  • Nakano, T., Kontani, K., Kurosu, H., Katada, T., Hoshi, M., and Chiba, K. (1999) G-protein betagamma subunit-dependent phosphorylation of 62-kDa protein in the early signaling pathway of starfish oocyte maturation induced by 1-methyladenine. Dev. Biol. 209, 200-209.  Abstract

 

  • Kishimoto, H., Hoshino, S., Ohori, M., Kontani, K., Nishina, H., Suzawa, M., Kato, S., and Katada, T. (1998) Molecular mechanism of human CD38 gene expression by retinoic acid. Identification of retinoic acid response element in the first intron. J. Biol. Chem. 273, 15429-15434.  Abstract


  • Scruel, O., Wada, T., Kontani, K., Sener, A., Katada, T., and Malaisse, W. J. (1998) Effects of D-glucose and starvation upon the cyclic ADP-ribose content of rat pancreatic islets. Biochem. Mol. Biol. Int. 45, 783-790.  Abstract
  • Inoue, S., Kontani, K., Tsujimoto, N., Kanda, Y., Hosoda, N., Hoshino, S., Hazeki, O., and Katada, T. (1997) Protein-tyrosine phosphorylation by IgG1 subclass CD38 monoclonal antibodies is mediated through stimulation of the FcgammaII receptors in human myeloid cell lines. J. Immunol. 159, 5226-5232.  Abstract


  • Hoshino, S., Kukimoto, I., Kontani, K., Inoue, S., Kanda, Y., Malavasi, F., and Katada, T. (1997) Mapping of the catalytic and epitopic sites of human CD38/NAD+ glycohydrolase to a functional domain in the carboxyl terminus. J. Immunol. 158, 741-747.  Abstract


  • Tsujimoto, N., Kontani, K., Inoue, S., Hoshino, S., Hazeki, O., Malavasi, F., and Katada, T. (1997) Potentiation of chemotactic peptide-induced superoxide generation by CD38 ligation in human myeloid cell lines. J. Biochem. (Tokyo) 121, 949-956.  Abstract


  • Kontani, K., Kukimoto, I., Kanda, Y., Inoue, S., Kishimoto, H., Hoshino, S., Nishina, H., Takahashi, K., Hazeki, O., and Katada, T. (1997) Signal transduction via the CD38/NAD+ glycohydrolase. Adv. Exp. Med. Biol. 419, 421-430.  Abstract
  • Kontani, K., Kukimonto, I., Kanda, Y., Inoue, S., Kishimoto, H., Hoshino, S., and Katada, T. (1996) Induction of CD38/NADase and its monoclonal antibody-induced tyrosine phosphorylation in human leukemia cell lines. Biochem. Biophys. Res. Commun. 222, 466-471.  Abstract

 

  • Hara-Yokoyama, M., Kukimoto, I., Nishina, H., Kontani, K., Hirabayashi, Y., Irie, F., Sugiya, H., Furuyama, S., and Katada, T. (1996) Inhibition of NAD+ glycohydrolase and ADP-ribosyl cyclase activities of leukocyte cell surface antigen CD38 by gangliosides. J. Biol. Chem. 271, 12951-12955.  Abstract
  • Matsuo, T., Hazeki, K., Tsujimoto, N., Inoue, S., Kurosu, H., Kontani, K., Hazeki, O., Ui, M., and Katada, T. (1996) Association of phosphatidylinositol 3-kinase with the proto-oncogene product Cbl upon CD38 ligation by a specific monoclonal antibody in THP-1 cells. FEBS Lett. 397, 113-116.  Abstract
  • Kukimoto, I., Hoshino, S., Kontani, K., Inageda, K., Nishina, H., Takahashi, K., and Katada, T. (1996) Stimulation of ADP-ribosyl cyclase activity of the cell surface antigen CD38 by zinc ions resulting from inhibition of its NAD+ glycohydrolase activity. Eur. J. Biochem. 239, 177-182.  Abstract
  • Kontani, K., Kukimoto, I., Nishina, H., Hoshino, S., Hazeki, O., Kanaho, Y., and Katada, T. (1996) Tyrosine phosphorylation of the c-cbl proto-oncogene product mediated by cell surface antigen CD38 in HL-60 cells. J. Biol. Chem. 271, 1534-1537.  Abstract


  • Inageda, K., Takahashi, K., Tokita, K., Nishina, H., Kanaho, Y., Kukimoto, I., Kontani, K., Hoshino, S., and Katada, T. (1995) Enzyme properties of Aplysia ADP-ribosyl cyclase: comparison with NAD glycohydrolase of CD38 antigen. J. Biochem. (Tokyo) 117, 125-131.  Abstract

 

  • Takahashi, K., Kukimoto, I., Tokita, K., Inageda, K., Inoue, S., Kontani, K., Hoshino, S., Nishina, H., Kanaho, Y., and Katada, T. (1995) Accumulation of cyclic ADP-ribose measured by a specific radioimmunoassay in differentiated human leukemic HL-60 cells with all-trans-retinoic acid. FEBS Lett. 371, 204-208.  Abstract


  • Ohoka, Y., Kontani, K., Iiri, T., Nishina, H., and Katada, T. (1995) Involvement of pertussis toxin-sensitive mechanism in retinoic acid-induced differentiation of human leukemic HL-60 cells. J. Biochem. (Tokyo) 117, 190-196.  Abstract
  • Chiba, K., Longo, F. J., Kontani, K., Katada, T., and Hoshi, M. (1995) A periodic network of G protein beta gamma subunit coexisting with cytokeratin filament in starfish oocytes. Dev. Biol. 169, 415-420.  Abstract


  • Katada, T., Kontani, K., Inanobe, A., Kobayashi, I., Ohoka, Y., Nishina, H., and Takahashi, K. (1994) Purification and separation of closely related members of pertussis toxin-substrate G proteins. Methods Enzymol. 237, 131-139.  Abstract

 

  • Kontani, K., Nishina, H., Ohoka, Y., Takahashi, K., and Katada, T. (1993) NAD glycohydrolase specifically induced by retinoic acid in human leukemic HL-60 cells. Identification of the NAD glycohydrolase as leukocyte cell surface antigen CD38. J. Biol. Chem. 268, 16895-16898.  Abstract


  • Chiba, K., Kontani, K., Tadenuma, H., Katada, T., and Hoshi, M. (1993) Induction of starfish oocyte maturation by the beta gamma subunit of starfish G protein and possible existence of the subsequent effector in cytoplasm. Mol. Biol. Cell. 4, 1027-1034.  Abstract


  • Kameyama, K., Haga, K., Haga, T., Kontani, K., Katada, T., and Fukada, Y. (1993) Activation by G protein beta gamma subunits of beta-adrenergic and muscarinic receptor kinase. J. Biol. Chem. 268, 7753-7758.  Abstract


  • Kontani, K., Takahashi, K., Inanobe, A., Ui, M., and Katada, T. (1992) Molecular heterogeneity of the beta gamma-subunits of GTP-binding proteins in bovine brain membranes. Arch. Biochem. Biophys. 294, 527-533.  Abstract
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