[Biology-U-L] [Fwd: Fall 2010 course on epigenetics]

Biology Undergraduate List biology-u-l at mentor.lscf.ucsb.edu
Thu Sep 16 09:22:08 PDT 2010

If you are a MCDB Major who has already completed MCDB 108ABC, please 
consider taking the following elective Chem 141 course.  Note that it 
would need to be officially petitioned to potentially count as MCDB 
major applicable.  Or, simply taken as an elective UCSB course.

Epigenetics Biochemistry 141

Professor Norbert Reich

Enrollment code: 49189

MWF, 9-9:50, Girvetz 1112

Text: Epigenetics, CSHL Press, Allis, Jenuwein, Reinberg & Caparros

This course covers the biology, biochemistry and therapeutic 
applications of the three basic epigenetic processes in prokaryotes and 
eukaryotes: DNA modification, chromatin modification, and silencing RNA.

·        Epigenetics in bacteria

·        Epigenetics in /Saccharomyces cerevisiae/

·        PEV, heterochromatin formation and gene silencing in /Drosophila/

·        Fungal models for epigenetics

·        RNAi and heterochromatin assembly

·        Epigenetic regulation in plants

·        Chromatin modifications and their mechanisms

·        Transcriptional silencing by polycomb/Trithorax group proteins

·        Histone variants and epigenetics

·        Epigenetic regulation of x chromosomes in /C. elegans/

·        Dosage compensation in /Drosophila/

·        Dosage compensation in mammals

·        DNA methylation in mammals

·        Genomic imprinting in mammals

·        Germ line and pluripotent stem cells

·        Nuclear transplantation and reprogramming of the genome

·        Epigenetics and human disease

·        Epigenetics and determinants of cancer

·        Epigenetic-based therapies

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